Prokaryotes and eukaryotes are classifications of organisms. Prokaryotes are single cell organism, such as bacteria. Eukaryotes, on the other hand, are multi cellular organisms, such as plants, animals, etc. There are a large number of structural differences between the two, especially in terms of organelle that are present. Eukaryotes have nucleus, mitochondria, lysosomes, endoplasmic recticulum, golgi apparatus, etc. Prokaryotes do not contain any of these cell organelle. Prokaryotes are much simpler in terms of structure and operation. In comparison, eukaryotes are very complex in terms of structure and functions. Prokaryotes are much smaller in size and are on the order of few micrometers. In comparison, eukaryotes are much bigger. The chromatin is spread though the cytoplasm in case of a prokaryotes. On the other hand, chromatin is enclosed in nuclear membrane in case of eukaryotes.
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